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Targeting B-Cell Maturation Antigen at Advanced Relapse in Multiple Myeloma

Oncology
Curriculum:
Targeting B-Cell Maturation Antigen at Advanced Relapse in Multiple Myeloma
Credits:
1.0 AMA PRA Category 1 Credit(s) 1.0 AANP Contact Hours 1.0 Pharmacology
Launch Date:
July 07, 2020
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Oncologists; hematologists; Nurse Practitioners (NPs); Physician Assistants (PAs); and other clinicians who care for patients being treated for oncological and hematological diseases.

Relevant Terms:

Rasim A. Gucalp, MD, FACP

Course Director and Moderator
Rasim A. Gucalp, MD, FACP
Professor, Department of Medicine (Oncology)
Albert Einstein College of Medicine
Director, Hematology/Oncology Fellowship Program
Montefiore Medical Center
Bronx, NY

Dr. Rasim Gucalp’s research interests include novel therapies in lung cancer as well as supportive care in cancer patients. He is actively involved in the multidisciplinary care of patients with lung cancer and central nervous system tumors. He is a member of several Montefiore Medical Center/Albert Einstein College of Medicine committees including the institutional tumor board, faculty senate, Pharmacy and Therapeutic Committee, and COGME.

 

A native of Turkey, Dr. Gucalp received his medical degree at Hacettepe University School of Medicine in Ankara, Turkey. After completing his medical residency at Downstate Medical Center in Brooklyn, he came to Montefiore Medical Center to complete his oncology fellowship. He is associate chairman of Department Oncology for educational activities and the director of the Hematology/Oncology Fellowship Program at Montefiore, and serves as a Professsor of Medicine at Albert Einstein College of Medicine.

Noah Kornblum, MD

Noah Kornblum, MD
Assistant Professor, Department of Medicine (Oncology)
Bone Marrow Transplant/Heme Malignancy
Montefiore Einstein Center for Cancer Care
Bronx, NY

Dr. Kornblum graduated from the Sackler School of Medicine in 1999. Dr. Kornblum works in Bronx, NY and 2 other locations and specializes in Medical Oncology. Dr. Kornblum is affiliated with Montefiore Medical Center Einstein Campus and Montefiore Medical Center.

1. Identify emerging treatment options for myeloma patients at advanced relapse.
2. Assess B-cell maturation antigen (BCMA) as a therapeutic target in patients at advanced relapse.
3. Compare the efficacy and safety of investigational agents targeting B-cell maturation antigen (BCMA) in relapsed myeloma patients.

This activity is presented by Albert Einstein College of Medicine-Montefiore Medical Center in Collaboration with NACE

Summary

Multiple myeloma (MM) remains an incurable hematological malignancy that is characterized by clonal proliferation of malignant plasma cells in the bone marrow. Despite major advances in therapy for MM, most patients eventually relapse and become refractory to further treatment. Immunotherapy holds great promise for producing a more durable response, as it is capable of harnessing the patient's own immune system to attack and destroy tumor cells.

One of the most promising immunotherapeutic strategies in MM today involves B-cell maturation antigen, or BCMA. Because BCMA-targeted immunotherapies are expected to transform the MM treatment paradigm, this video-based activity reviews the latest research advances so that clinicians may continue providing optimal care for their patients.

 

Planning Committee
Sandy Bihlmeyer, M.Ed.
Senior Project Manager
 
Michelle Frisch, MPH, CHCP
Vice President, Operations
 
Daniela Hiedra
Associate Program Manager
 
Gregg Sherman, MD
Chief Medical Officer
 
Deborah Paschal, CRNP
Clinical Nurse Practitioner
Philadelphia, PA
 
Donald Harting MA, MS, ELS, CHCP
CME Content Development Specialist
Harting Communications LLC
Downingtown, PA
 
Peer Reviewer
Amit Verma, MBBS
Professor, Department of Medicine (Oncology)
Professor, Department of Developmental & Molecular Biology
Albert Einstein College of Medicine
Director, Division of Hemato-Oncology, Montefiore Department of Oncology
Bronx, NY
 
Policy on Faculty and Provider Disclosure
It is the policy of Albert Einstein College of Medicine-Montefiore Medical Center and NACE to ensure fair balance, independence, objectivity and scientific rigor in all activities. All faculty participating in CME/CE activities are required to present evidence-based data, identify and reference off-label product use and disclose all relevant financial relationships. All planners are also required to disclose all relevant financial relationships. The ACCME defines a commercial interest as an entity producing, marketing, re-selling, or distributing health care goods or services consumed by or used on patients. The ACCME does not consider providing clinical service directly to patients to be commercial interests - unless the provider of the clinical service is owned, or controlled by, an ACCME-defined commercial interest. 
 
Disclosures
Dr. Gucalp has no relevant conflicts of interest with any ACCME-defined commercial interest.
Dr. Kornblum has no relevant conflicts of interest with any ACCME-defined commercial interest.
Ms. Bihlmeyer has no relevant conflicts of interest with any ACCME-defined commercial interest.
Ms. Frisch has no relevant conflicts of interest with any ACCME-defined commercial interest.
Mr. Harting has disclosed the following financial relationships: Stock in Bio-Rad Laboratories, Laboratory Corporation of America, Merck & Co Inc, Moderna Inc., ThermoFisher Scientific
Ms. Hiedra has no relevant conflicts of interest with any ACCME-defined commercial interest.
Ms. Paschal has no relevant conflicts of interest with any ACCME-defined commercial interest.
Dr. Sherman has no relevant conflicts of interest with any ACCME-defined commercial interest.
Dr. Verma has no relevant conflicts of interest with any ACCME-defined commercial interest.
 
Accreditation Statement: CME Provider
In support of improving patient care, Albert Einstein College of Medicine-Montefiore Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
 
 
Credit Designation Statement
Albert Einstein College of Medicine-Montefiore Medical Center designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity was planned by and for the healthcare team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change.
 
 
Accreditation Statement: AANP Provider
National Association for Continuing Education is approved as a provider of nurse practitioner continuing education by the American Association of Nurse Practitioners. AANP Provider Number 121222. This program has been approved for 1.0 contact hour of continuing education, which includes 1.0 pharmacology hour.
 
Disclosure of Unlabeled/Unapproved Uses of Products
This presentation will reference the unlabeled/unapproved use of belantamab mafodotin, an anti BCMA CAR T-cell therapy, in relapsed myeloma patients.
 
Statement of Commercial Support
This activity is supported by an educational grant from GlaxoSmithKline, LLC.
 

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Privacy

Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development protects the privacy of personal and other information regarding participants and educational collaborators. We will not release personally identifiable information to a third party without the individual's consent, except such information as is required for reporting to the ACCME.

Albert Einstein College of Medicine-Montefiore Medical Center, Center for Continuing Professional Development maintains physical, electronic, and procedural safeguards that comply with federal regulations to protect against the loss, misuse, or alteration of information collected from you.

Additional information regarding Albert Einstein College of Medicine-Montefiore Medical Center's Privacy Policy can be viewed at https://www.mecme.org/PrivacyStatement.aspx.


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