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The Science and Strategies Behind Successful MS Diagnosis

Neurology
Curriculum:
Does This Patient Have MS? Applying the 2017 McDonald Criteria to Make an Early, Accurate Diagnosis
Credits:
0.50 AMA PRA Category 1 Credit(s)™ 0.50 ANCC Contact Hours
Launch Date:
December 19, 2019
Expiration Date:
December 19, 2020

Primary Audience:

Neurologists and neurology nurses

Relevant Terms:

Multiple Sclerosis

Ilya Kister, MD

Associate Professor, Department of Neurology
NYU Langone Health
NYU Langone Multiple Sclerosis Comprehensive Care Center
New York, NY

Dr. Kister earned his medical degree from Mount Sinai School of Medicine in 2002. He completed his residency in neurology at Albert Einstein College of Medicine in 2006 and his fellowship in multiple sclerosis at NYU Medical Center in 2007. Currently he is associate professor, department of neurology, and director, neuromyelitis optica treatment and research program, at NYU Langone in New York City. He is a widely published author and is fluent in several languages, including Russian.

Stephen Krieger, MD

Associate Professor of Neurology
Corinne Goldsmith Dickinson Center for MS
Icahn School of Medicine at Mount Sinai
New York, NY

Stephen Krieger joined The Corinne Goldsmith Dickinson Center for MS as a fellow in multiple sclerosis after completing his neurology residency training at Mount Sinai. He was the recipient of a 2006 American Academy of Neurology Scholarship and received a Sylvia Lawry Fellowship in clinical research from the National Multiple Sclerosis Society. He was graduated from Columbia College and received his MD degree from Yale University. Dr Krieger has a clinical practice at the Center and has participated in numerous MS clinical trials, including oral therapies and monoclonal antibodies used as disease modifying agents for MS. In addition to his clinical work, he has an academic appointment as associate professor of neurology at the Icahn School of Medicine at Mount Sinai, where he is director of the neurology residency training program. He has also served as director of the Brain and Behavior seminar series for the medical school. Dr Krieger was elected as a Faculty Member of Alpha Omega Alpha and inducted as a Fellow into the Institute for Medical Education in 2011, and has received several subsequent teaching and mentorship awards including the George Forster Compassion Award in 2014. Dr Krieger is on several advisory boards and steering committees in the field of MS and is an active member of the American Academy of Neurology (AAN), which awarded him an A.B. Baker teaching recognition award in 2010. He has presented original work at AAN, CMSC, ACTRIMS, and ECTRIMS and has written review articles on and lectures nationally about MS with an emphasis on emerging therapies. In 2015, Dr Krieger proposed the topographical model of MS, a new conceptualization of MS disease course that was accepted for presentation at several national/international meetings and was the subject of an article in Scientific American

Andrew J. Solomon, MD

Associate Professor, Department of Neurological Sciences
Division Chief, Multiple Sclerosis
The University of Vermont
Burlington, VT

Andrew J. Solomon, MD, is an Associate Professor and Division Chief of multiple sclerosis (MS) at the University of Vermont (UVM) Department of Neurological Sciences in Burlington, VT. Dr.Solomon earned his medical degree from Mount Sinai School of Medicine in New York, NY where he participated in the Humanities and Medicine Program and also graduated with Distinction in Research. He completed his internship in internal medicine, his residency in neurology, and his fellowship in multiple sclerosis and neuroimmunology at Oregon Health & Science University and the Portland VA Medical Center in Portland, OR. At the UVM MS Center, Dr. Solomon is an investigator on numerous local and national multicenter clinical and translational studies evaluating therapeutic and prognostic interventions for MS. Dr.Solomon has been recognized nationally and internationally for his research on MS diagnosis and misdiagnosis. His current work focuses on the evaluation of novel diagnostic imaging and laboratory biomarkers for MS.

1. Describe the clinical features, imaging findings, and laboratory results that support and that do not support a diagnosis of multiple sclerosis (MS).
2. Detail the key components of the 2017 revisions to the McDonald criteria, and when and how those criteria should be employed in assessing patients for MS.  
3. Outline an evaluation strategy for correctly diagnosing MS.

Accreditation
Jointly provided by Global Education Group and Global Academy for Medical Education.

Target Audience
Neurology clinicians involved in the diagnosis of patients with multiple sclerosis (MS), including physicians, physician assistants (PAs), nurse practitioners (NPs), and nurses.
 

Learning Objectives
At the conclusion of this activity, participants should be better able to:

  • Describe the clinical features, imaging findings, and laboratory results that support and that do not support a diagnosis of multiple sclerosis (MS).
  •  Detail the key components of the 2017 revisions to the McDonald criteria, and when and how those criteria should be employed in assessing patients for MS.
  • Outline an evaluation strategy for correctly diagnosing MS.

Activity Description
In this interactive online activity, experts discuss recent updates to the McDonald MS diagnostic criteria, how to apply them to their patients with neurological symptoms, and how to avoid potential pitfalls when doing so.

Statement of Educational Need
The accuracy and speed required to diagnose multiple sclerosis depends largely on the acumen and the expertise of the clinician. The ability to accurately interpret MRI findings is essential. Too often, the diagnosis is missed or the patient’s neurological condition is misidentified, leading to delays in offering appropriate therapy and posing an increased risk for disability progression.

Conflict of Interest Policy/Disclosure Statement
Global Education Group (Global) requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

Faculty Disclosures
Ilya Kister, MD:
Consultant/Independent Contractor: F. Hoffmann-La Roche, Genentech, Arcus
Medica, GrandRounds
Grant/Research Support: F. Hoffmann-La Roche, Genentech, Biogen Idec

Stephen Krieger, MD:
Consultant/Independent Contractor: Biogen, EMD Serono, Genentech,
Genzyme, Mallinckrodt, MedDay, Novartis, Teva, TG Therapeutics
Honoraria: Biogen, EMD Serono, Novartis

Andrew J. Solomon, MD:
Consultant/Independent Contractor: Biogen, EMD Serono
Grant/Research Support: Biogen
Advisory Board: EMD Serono

Planners/Managers
The following Global Education Group planners and managers have nothing to disclose: Lindsay Borvansky, Ashley Marostica, Andrea Funk, Liddy Knight, Ashley Cann.

The following Global Academy for Medical Education planners and managers have nothing to disclose: Tom Garry, Ron Schaumberg, Nicola Sirdevan.

Accreditation Statement
This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Global Academy for Medical Education. Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation
Global Education Group designates this enduring activity for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurse Credit Designation
Global Education Group is accredited with distinction as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. This educational activity for 0.5 contact hour is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Fee Information
There is no fee for this educational activity.

Instructions for Receiving Credit
In order to receive credit for this activity, participants must complete the activity. Participants must also score at least 70% on the posttest and complete the activity evaluations.

Statement of Commerical Support
This activity is supported by educational grants from Biogen MA, Inc. and Genentech, Inc.

Disclaimer Statement/Disclosure of Unlabeled Use
Disclosure of Unlabeled Use: This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Global Academy for Medical Education do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer: Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Contact Information
For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com

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