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ADPKD - What Your Patients Want You to Know

Understanding Patients' Perspectives to Improve ADPKD Awareness, Diagnosis, and Management
.50 AMA PRA Category 1 Credit(s) .50 ANCC Contact Hours
Launch Date:
December 31, 2018
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Nephrologists; primary care clinicians

Relevant Terms:

Hypertension genetic conditions, pain, diet, depression, multidisciplinary care

Neera K. Dahl, MD, PhD

Associate Professor of Nephrology

Yale University School of Medicine

New Haven, Connecticut

Neera K. Dahl, MD, PhD, is Associate Professor, Section of Nephrology, at Yale University School of Medicine in New Haven, Connecticut, where she also serves as director of the nephrology clinical trials program. She is medical director for DaVita Dialysis, also in New Haven. She earned her medical degree at Tufts University School of Medicine in Boston, Massachusetts, and her doctorate in physiology at Sackler School of Biomedical Science, also at Tufts.

Brittany P. Cavanaugh, DO

Professor of Internal Medicine

Yale University School of Medicine

New Haven, Connecticut

Brittany P. Cavanaugh, DO, is an internal medicine primary care physician with Yale Health Center, New Haven, Connecticut. She earned her doctorate at Ohio University Heritage College of Osteopathic Medicine in Athens, Ohio and completed her residency in internal medicine at University of Louisville in Louisville, Kentucky.



1. Identify clinical approaches for the early recognition, efficient evaluation, and timely diagnosis of autosomal dominant polycystic kidney disease (ADPKD)
2. Identify data-driven approaches to the comprehensive care of patients with ADPKD
3. Recognize which patients with ADPKD are most likely to benefit from currently available and emerging therapies for ADPKD

Although autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic disorder leading to end-stage renal disease (ESRD), significant gaps exist in physicians’ knowledge of the disease and, consequently, in their ability to manage patients with ADPKD in their practice.1 Indeed, an international panel of experts convened to identify gaps and questions affecting clinicians’ approach to the condition detailed 48 separate topics that require attention to improve the care of patients with ADPKD.1

Effectively addressing those gaps encompasses educating primary care clinicians, nephrologists, and genetic counselors, each of whom plays a key role in the care of patients with ADPKD.

“There is ample evidence to suggest that primary care providers (PCPs) do not have adequate training and knowledge about ADPKD, and not all newly diagnosed patients are referred automatically to a nephrologist,” according to the international experts participating in the Kidney Disease—Improving Global Outcomes (KDIGO) Controversies Conference on ADPKD.This is a significant shortcoming given that the condition increasingly is seen in the primary care setting, according to two nurse practitioners who note that PCPs “must be able to identify and effectively care for patients with this condition.2

Nephrologists also have significant knowledge and practice gaps that must be addressed. “Diagnosis, evaluation, prevention, and treatment vary widely, and there are no broadly accepted practice guidelines,” according to the KDIGO panelists.1 They added, “Many nephrologists lack time and ability to explain the diagnosis and all of its complex implications” to patients.1

Similarly, the panelists noted that, “With increasing availability of genetic testing and clinical relevance of such testing for prognosis, physicians and [genetic] counselors will need to be trained to communicate the potential benefits and limitations of these analyses.1

This continuing medical education activity was developed to address those needs.

1. Chapman AB, Devuyst O, Eckardt K-U, et al. Autosomal dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2015;88:17-27.

2. Yrad ALS, Humphreys C. Primary care perspectives in autosomal dominant polycystic kidney disease. Nurse Pract. 2017;42:8-11.

Jointly provided by

in partnership with
This activity is supported by an independent educational grant from Otsuka America Pharmaceutical, Inc.

Term of Offering

This activity was released on 12/31/18 and is valid for one year. Requests for credit must be made no later than 12/31/19.

Target Audience

The educational design of this activity addresses the needs of nephrology and primary care providers involved in the treatment of patients with ADPKD.

Physician Accreditation Statement

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Global Education Group (Global) and Global Academy for Medical Education. Global is accredited by the ACCME to provide continuing medical education for physicians.

Physician Credit Designation

Global Education Group designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nursing Continuing Education

Global Education Group is accredited with distinction as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

This educational activity for 0.5 contact hours is provided by Global Education Group. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

Global Contact Information

For information about the accreditation of this program, please contact Global at 303-395-1782 or cme@globaleducationgroup.com.

Instructions to Receive Credit

In order to receive credit for this activity, the participant must read the activity information, review the activity in its entirety, and complete the online post-test and evaluation. Upon completing this activity as designed and achieving a passing score on the post-test, you will be directed to a web page that will allow you to receive your certificate of credit via e-mail or you may print it out at that time.

Fee Information & Refund/Cancellation Policy

There is no fee for this educational activity.

Disclosure of Conflicts of Interest

Global Education Group (Global) requires instructors, planners, managers and other individuals and their spouse/life partner who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by Global for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:


Name of Faculty or Presenter

Reported Financial Relationship

Brittany P. Cavanaugh, DO

Nothing to disclose

Neera Dahl, MD

Has been a Consultant/Independent Contractor and a member of the Speakers’ Bureau for Otsuka America Pharmaceutical, Inc.


The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:


Name of Planner or Manager

Reported Financial Relationship

Lindsay Borvansky

Nothing to disclose

Ashley Cann

Nothing to disclose

Andrea Funk

Nothing to disclose

Tom Garry

Nothing to disclose

Shirley V. Jones, MBA

Nothing to disclose

Liddy Knight

Nothing to disclose

Mike LoPresti

Nothing to disclose

Ashley Marostica, RN, MSN

Nothing to disclose

Ron Schaumburg

Nothing to disclose


Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Global Education Group (Global) and Global Academy for Medical Education do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of any organization associated with this activity. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed in this activity should not be used by clinicians without evaluation of patient conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Copyright © 2018 by Global Academy for Medical Education, LLC, Frontline Medical Communications, Inc. and its Licensors. All rights reserved. No part of this publication may be reproduced or transmitted in any form, by any means, without prior written permission of the Publisher. Global Academy for Medical Education, LLC, the accredited provider or the Publisher will not assume responsibility for damages, loss, or claims of any kind arising from or related to the information contained in this publication, including any claims related to the products, drugs, or services mentioned herein.


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