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Individualizing Therapy in Patients with Heart Failure

Current and Emerging Treatment Options for Patients with Chronic Heart Failure
1 AMA PRA Category 1 Credit(s)
Launch Date:
November 24, 2015
Expiration Date:
The accreditation for this activity has expired.

Primary Audience:

Cardiologists, Primary Care Physicians, Hospitalists, Internal Medicine Physicians

Relevant Terms:

Chronic heart failure, heart failure

Mariell L. Jessup, MD

Mariell L. Jessup, MD
Professor of Medicine
University of Pennsylvania School of Medicine
Philadelphia, PA

Dr. Jessup, who is board certified in Internal Medicine, Cardiovascular Disease and Advanced Heart Failure and Transplant Cardiology, is Professor of Medicine at the University of Pennsylvania School of Medicine, Associate Chief-Clinical Affairs, Cardiovascular Division of Medicine, and Medical Director of the Heart and Vascular Center at Penn Medicine, where she works with a multi-disciplinary team of cardiologists, cardiac and vascular surgeons, nurse practitioners, and nurses to deliver collaborative, cutting-edge care to patients. Dr. Jessup’s focus throughout her career has been on the optimal management of patients with heart failure, including the appropriate selection of patients for heart transplant or ventricular assist devices.
She has been a member of the committee to revise ACC/AHA Guidelines for the Management of Heart Failure, published in 2001 and most recently in 2005. She was the Chair of the ACC/AHA Guidelines focused update for heart failure published in March, 2009. She is now the Vice-Chair of that same committee. Dr. Jessup served on the American Heart Association’s Council of Clinical Cardiology Program Committee, and was a member-at-large on the AHA annual meeting’s program committee. She served for two years as the Chair of the Committee for Scientific Sessions Program of the AHA. She is a member of the Board of Directors of the national AHA and became President of the American Heart Association in June of 2013. She completed a 4-year term as an ABIM representative for the Residency Review Committee-Internal Medicine of the ACGME, and a 6-year term on the ABIM’s Cardiovascular Board. Dr. Jessup is currently the Chair of ABIM’s Cardiovascular Specialty Board. She joined the inaugural Board of the Advanced Heart Failure and Transplant cardiology secondary subspecialty, and served as Chair from June 2012 to 2014. She served as the Co-chairman of the ISHLT’s Heart Failure Council, and served on the Board of Directors of the ISHLT for three years. She was a member of the Executive Council of the Heart Failure Society of America, and served as the secretary for the HFSA. She is on the Steering committee of the INTERMACs registry for ventricular assist devices.
Dr. Jessup has published numerous articles as well as editorials, reviews, chapters and reports from committees on heart failure, as well as heart transplant. She has been recognized by The Best Doctors in America and in Philadelphia Magazine’s Top Docs issue.
Dr. Jessup received her Bachelor of Arts degree from the University of Pennsylvania and a medical degree from Hahnemann Medical College in Philadelphia. She completed her residency in internal medicine at Hahnemann University Hospital and a cardiovascular fellowship at the Hospital of the University of Pennsylvania.

Javed Butler, MD MPH FACC FAHA

Javed Butler, MD MPH FACC FAHA
Chief of Cardiology
Co-Director, Heart Institute
Professor of Medicine
Stony Brook University
Stony Brook, NY

Dr. Butler is the chief of cardiology and co-director of the heart institute at the Stony Brook University. He is board certified in internal medicine, cardiovascular medicine, and advanced heart failure and transplant medicine. Prior to joining Stony Brook, he was professor of medicine at the Emory University. Dr. Butler has published over 220 peer-reviewed publications. Dr. Butler is the recipient of the Simon Dack Award by the American College of Cardiology and the Time, Feeling, and Focus award by the American Heart Association. He has been cited in America's Best Doctors numerous times. He serves on the ACC/AHA heart failure guidelines committee, on several NIH study sections, chairs the NIH heart failure network's ancillary studies committee; and he is a member of the executive council of the Heart Failure Society of America. He serves on the editorial board of several peer reviewed cardiovascular journals. 

After completing his residency at Yale, cardiology fellowship and advanced heart failure and transplant fellowship at Vanderbilt, and cardiac imaging fellowship from the Massachusetts General Hospital. Prior to joining Emory, he served as the director of the cardiac and heart-lung transplant programs at Vanderbilt. He has completed Masters degree in Public Health from Harvard University and is currently pursing Masters in Business Administration from Emory University.

Gregg Fonarow, MD, FACC, FAHA

Gregg Fonarow, MD, FACC, FAHA
Professor of Medicine, Co-Chief
UCLA Division of Cardiology
Director, Ahmanson-UCLA Cardiomyophathy Center
Los Angeles, CA

Gregg C. Fonarow, MD, FACC, FAHA is the Eliot Corday Professor of Cardiovascular Medicine and Science at UCLA. He serves as Director of the Ahmanson-UCLA Cardiomyopathy Center, Co-Director of UCLA's Preventative Cardiology Program, and Clinical Co-Chief of Cardiology, UCLA Division of Cardiology. He attained the rank of Professor of Medicine, Geffen School of Medicine at UCLA in 2003. His research interests center on acute and chronic heart failure, preventative cardiology, quality of care, outcomes, and implementing treatment systems to improve clinical outcome. Dr. Fonarow has published over 600 research studies and clinical trials in heart failure, disease management, preventative cardiology, and outcomes research. New therapies and management strategies for advanced heart failure and research into the pathophysiology of this disease are conducted at UCLA under his direction. He has also developed and successfully implemented a comprehensive atherosclerosis treatment program at the UCLA Medical Center (Cardiovascular Hospitalization Atherosclerosis Management Program: CHAMP), which served as the model for the American Heart Association's Get With The Guidelines Program. Dr. Fonarow is a past chair of the steering committee for AHA Get With The Guideline's Program and the ACC ACTION Registry-GWTG. He also chaired ADHERE, OPTIMIZE-HF, and IMPROVE-HF performance improvement registries. He is on the steering committee and serves as an investigator for a number of ongoing randomized clinical trials in heart failure. He serves as a reviewer and serves on the editorial boards for a number of leading cardiovascular journals. Dr. Fonarow received the outstanding UCLA Cardiology Faculty Teaching Award in 1997 and was honored by the American College of Cardiology with the W. Proctor Harvey Young Teacher Award in 1998. He received an AHA Award of Meritorious Achievement in 2004. In 2009, he received the Raymond D. Bahr Award of Excellence and the Turning Guidelines into Lifelines Award from the AHA. In 2014, Dr. Fonarow was selected by Thomson Reuters for the list of Highly Cited Researchers, which identifies the world's most influential contemporary researchers across 21 scientific fields with the greatest number of published articles that received marks for exceptional impact. In 2015, Dr. Fonarow received a Clinical Research Forum Distinguished Clinical Achievement Award.
1. Describe the pathophysiology and impact of heart rate on heart failure morbidity and mortality in patients with systolic heart failure.
2. Implement current optimal medical therapy for the treatment of chronic congestive heart failure
3. Discuss the role of vasoactive peptides and If channel in the regulation of the cardiovascular system
4. Assess current data and potential role of new and emerging therapies for the treatment of heart failure with reduced ejection fraction

This activity was launched on November 24, 2015 and will expire on November 24, 2016.
This activity has been designed to meet the educational needs of cardiologists and internists with a sub-specialty in cardiology, primary care clinicans, NPs, PAs and other health care professionals involved in the care of patients with heart failure.

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the providership of Horizon CME. Horizon CME is accredited by the ACCME to provide continuing medical education for physicians (provider renewal in July 2016.)

Horizon CME designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
By reviewing the course content and successfully completing the post-test and evaluation, physicians are entitled to receive 1.0 AMA PRA category 1 credits™. Statement of credit will be available to print from your user history page.
  • Read the learning objectives and faculty disclosures.
  • Participate in the activity.
  • Complete the post-test and activity evaluation.
  • Physicians who successfully complete the post-test and evaluation will receive CME credit. You must score with an 75% or higher on the post-test to receive credit for this activity.
  • All other participants who successfully complete the post-test and evaluation will receive a certificate of participation.

Horizon CME requires instructors, planners, managers and other individuals who are in a position to influence the content of this activity to disclose any real or apparent conflict of interest (COI) which may arise as a result of prospective faculty members' relevant relationships with drug or device manufacturer(s). Horizon CME is committed to resolving all conflicts of interest and retaining only those speakers with financial interest conflicts that can be reconciled with the goals and educational integrity of the CME activity.
Name of Faculty Reported Financial Relationship
Mariell Jessup, MD
Dr. Jessup does not have any financial relationships with any entity marketing, selling, or producing health care goods or services.
Javed Butler, MD, MPH, FAHA, FACC Dr. Butler has been a consultant for Amgen, Bayer, Cardiocell, Celladon, Jannsen, Novartis, Relypsa, Stealth, Peptide,Trevena, Z Pharma, and Zensun. He is also on the speakers bureau for Novartis. Additionally, he has received research grants from NIH and the European Union.
Gregg Fonarow, MD, FACC, FAHA
Dr. Fonarow has consulted for Amgen, Janssen, Medtronic, and Novartis and has received research grants from National Institutes of Health (NIH) and Medtronic.
The planners and managers reported the following financial relationships or relationships they or their spouse/life partner have with commercial interests related to the content of this continuing education activity:

The following Horizon CME planners and managers, Brian Lee, PharmD, Cara Williams, PharmD, and Elizabeth Wilkerson hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
This activity is supported by educational funding provided by Amgen.

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. 
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners.  Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

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